Breyer Capital is Leading the Series A Financing of Paige:AI

MOQIPEOPLE INSIDER is Honored to Announce that Breyer Capital is Leading the Series A Financing of Paige:AI 

#VC #Startup #AI #Pathology #MedicalTech


A true visionary – prominent investor in the world, Mr. Breyer and his firm, Breyer Capital, are leading a $25 million Series A round for Paige.AI , a New York-based startup applying AI to pathology to improve diagnosis and treatment of cancer. 

Introducing Paige.AI

Paige.AI has signed a comprehensive license with the Memorial Sloan Kettering Cancer Center (MSK) to gain exclusive access to its intellectual property in computational pathology, as well as exclusive rights to its library of 25 million pathology slides. The de-identified data set is one of the world’s largest tumor pathology archives, the company said.

The company will be fully integrated into lab information systems by using the library to develop machine learning applications which is developing computational programs across diagnostic pathology and clinical annotations and anonymized genomic sequencing results such as starting with breast, prostate and other major cancers, according to a company press release.

“Over the next decade there will be several companies in the fields of artificial intelligence and medicine that will provide enormous investment returns and at the same time make fundamental differences in patients’ and doctors’ lives,” Mr. Breyer said.Screen Shot 2018-02-28 at 7.25.38 AMPathology is at the cornerstone of most cancer diagnoses, yet most pathologic diagnoses rely on manual, subjective processes developed ages ago. While slide digitization has been around for over a decade, it has failed to gain traction because digital slides alone have done little to improve workflows.

Computational pathology will provide the missing link in the adoption of digital pathology, moving this vital field forward with support tools to help pathologists make decisions with greater speed, accuracy, objectivity and reproducibility — and at a lower cost. Armed with AI enabled systems, pathologists will spend less time compiling data and more time interpreting data. They will better understand how a patient’s diagnosis affects treatment and recovery.


In 2018 PAIGE’s slide viewer was rolled out institution-wide at Memorial Sloan Kettering Cancer Center and is the single entry point for pathologists and cancer researchers.

“I believe we are entering the market with three core assets: better data, better expertise, and better people.” Mr. Breyer said.

Data: Successful AI systems rely on a massive amount of data to train robust, reproducible algorithms. Paige.AI has a partnership with Memorial Sloan Kettering Cancer Center (MSK) and has exclusive access to all of MSK’s intellectual property in the field of computational pathology as well as exclusive rights to their library of 25 million pathology slides.

Domain Expertise: Raw image data is not enough to excel in complex pathology tasks. A successful AI must be trained on the highest quality (clinician-generated) domain-specific annotations. Paige.AI is innovating the annotation process, not only by developing dedicated annotation tools, but also by incorporating de-identified clinical data, treatment data, genomic analysis and survival data into comprehensive deep learning models.

Exceptional Talent: Paige.AI’s ML team of PhDs and computation experts is led by the founding father of Computational Pathology: Thomas Fuchs. Fuchs is the director of Computational Pathology in The Warren Alpert Center for Digital and Computational Pathology at MSK, and professor at Weill-Cornell, where he teaches Machine Learning. Dr. Fuchs published the first Computational Pathology paper in 2008, a review of the field in 2011 and more than 90 publications in machine learning and medicine.




From health care and financial services to mobility and cybersecurity, start-ups that utilize artificial intelligence are some of the world’s hottest VC bets. Where do investors see AI’s greatest potential — and its potential shortcomings — today and far into the future?

Jim Breyer, Founder and C.E.O., Breyer Capital & Deep Nishar, Senior Managing Partner, SoftBank Vision Fund In conversation with Rebecca Blumenstein.

Read more info via:


Fashion Tech Sweater for Winter – Engineers Develop Floating Solar Fuels Rig for Seawater Electrolysis


#FashionTech #MOQIFashionTechActiveWear #ScienceTech


Fashion Tech Sweater for Winter – Engineers Develop Floating Solar Fuels Rig for Seawater Electrolysis

Two mesh electrodes are held at a narrow separation distance (L), and generate H2 and O2 gases concurrently. The key innovation is the asymmetric placement of the catalyst on the outward facing surfaces of the mesh, such that the generation of bubbles is constrained to this region. When the gas bubbles detach, their buoyancy causes them to float upward into separate collection chambers.Image credit: Credit: Daniel Esposito/Columbia Engineering

Screen Shot 2018-01-23 at 1.48.17 AM

In a single hour, more energy from the sun hits the Earth than all the energy used by humankind in an entire year. Imagine if the sun’s energy could be harnessed to power energy needs on Earth, and done in a way that is economical, scalable, and environmentally responsible. Researchers have long seen this as one of the grand challenges of the 21st century.

Daniel Esposito, assistant professor of chemical engineering at Columbia Engineering, has been studying water electrolysis?the splitting of water into oxygen (O2) and hydrogen (H2) fuel?as a way to convert electricity from solar photovoltaics (PVs) into storable hydrogen fuel. Hydrogen is a clean fuel that is currently used to propel rockets in NASA’s space program and is widely expected to play an important role in a sustainable  future. The vast majority of today’s hydrogen is produced from natural gas through a process called steam methane reforming that simultaneously releases CO2, but water electrolysis using electricity from solar PV offers a promising route to produce H2 without any associated CO2 emissions.

Esposito’s team has now developed a novel photovoltaic-powered electrolysis device that can operate as a stand-alone platform that floats on open water. His floating PV-electrolyzer can be thought of as a “solar fuels rig” that bears some resemblance to deep-sea oil rigs, except that it would produce hydrogen fuel from sunlight and water instead of extracting petroleum from beneath the sea floor. The study, “Floating Membraneless PV-Electrolyzer Based on Buoyancy-Driven Product Separation,” was published today by International Journal of Hydrogen Energy.

The researchers’ key innovation is the method by which they separate the H2 and O2 gasses produced by water electrolysis. State-of-the-art electrolyzers use expensive membranes to maintain separation of these two gases. The Columbia Engineering device relies instead on a novel  configuration that allows the gases to be separated and collected using the buoyancy of bubbles in water. The design enables efficient operation with high product purity and without actively pumping the electrolyte. Based on the concept of buoyancy-induced separation, the simple electrolyzer architecture produces H2 with purity as high as 99 percent.

“The simplicity of our PV-electrolyzer architecture?without a membrane or pumps?makes our design particularly attractive for its application to seawater electrolysis, thanks to its potential for low cost and higher durability compared to current devices that contain membranes,” says Esposito, whose Solar Fuels Engineering Laboratory develops solar and electrochemical technologies that convert renewable and abundant solar energy into storable chemical fuels. “We believe that our prototype is the first demonstration of a practical membraneless floating PV-electrolyzer system, and could inspire large-scale ‘solar fuels rigs’ that could generate large quantities of H2  from abundant sunlight and seawater without taking up any space on land or competing with fresh water for agricultural uses.”

Commercial electrolyzer devices rely on a membrane, or divider, to separate the electrodes within the device from which H2 and O2 gas are produced. Most of the research for electrolysis devices has been focused on devices that incorporate a membrane. These membranes and dividers are prone to degradation and failure and require a high purity water source. Seawater contains impurities and microorganisms that can easily destroy these membranes.

“Being able to safely demonstrate a device that can perform electrolysis without a membrane brings us another step closer to making seawater electrolysis possible,” says Jack Davis, the paper’s first author and a PhD student working with Esposito. “These solar fuels generators are essentially artificial photosynthesis systems, doing the same thing that plants do with photosynthesis, so our device may open up all kinds of opportunities to generate clean, renewable energy.”

Crucial to the operation of Esposito’s PV-electrolyzer is a novel electrode configuration comprising mesh flow-through electrodes that are coated with a catalyst only on one side. These asymmetric electrodes promote the evolution of gaseous H2 and O2 products on only the outer surfaces of the electrodes where the catalysts have been deposited. When the growing H2 and O2 bubbles become large enough, their buoyancy causes them to detach from the electrode surfaces and float upwards into separate overhead collection chambers.

The team used the Columbia Clean Room to deposit platinum electrocatalyst onto the mesh electrodes and the 3D-printers in the Columbia Makerspace to make many of the reactor components. They also used a high-speed video camera to monitor transport of H2 and O2 bubbles between electrodes, a process known as “crossover.” Crossover between electrodes is undesirable because it decreases product purity, leading to safety concerns and the need for downstream separation units that make the process more expensive.

In order to monitor H2 and O2 crossover events, the researchers incorporated windows in all of their electrolysis devices so that they could take high-speed videos of gas bubble evolution from the electrodes while the  was operating. These videos were typically taken at a rate of 500 frames per second (a typical iPhone captures video at a rate of 30 frames per second).

The team is refining their design for more efficient operation in real seawater, which poses additional challenges compared to the more ideal aqueous electrolytes used in their laboratory studies. They also plan to develop modular designs that they can use to build larger, scaled-up systems.

Esposito adds: “There are many possible technological solutions to achieve a sustainable energy future, but nobody knows exactly what specific technology or combination of technologies will be the best to pursue. We are especially excited about the potential of  technologies because of the tremendous amount of solar energy that is available. Our challenge is to find scalable and economical technologies that convert sunlight into a useful form of energy that can also be stored for times when the sun is not shining.”

The study is titled “Floating Membraneless PV-Electrolyzer Based on Buoyancy-Driven Product Separation.”

More information: “Floating Membraneless PV-Electrolyzer Based on Buoyancy-Driven Product Separation,” International Journal of Hydrogen Energy (2017). , DOI: 10.1016/j.ijhydene.2017.11.086

Provided by: Columbia University School of Engineering and Applied Science


Visa Offering Startups up – The Everywhere Initiative


Visa Offering Startups up – The Everywhere Initiative: Three $50,000 Challenges. You Must Act Fast – Submission is Now Open through May 26, 2016.


Now in its second year, Visa’s The Everywhere Initiative is awarding up to $150k to three deserving startups solving important business challenges. Each winning company will get up to $50k and work alongside Visa to implement its idea on the corporation’s global platform.

Wherever you want to be, Visa is going to help you get there. In its second-annual Everywhere Initiative we will once again present three real-life business challenges for startups to help solve. If you’re a startup, apply now for a chance to win pilot money and an opportunity to work directly with Visa and co-create innovative solutions that help consumers achieve their goals. Submission is now open through May 26, 2016.

Recognizing the importance of getting feedback quickly with a pilot, Visa is directly investing in promising ideas without taking equity in a low-risk, low-barrier, frictionless way. Visa wants to work with the most promising ideas and entrepreneurs and is ready to leverage its presence as an innovation leader in order to do so.


Read more via: